1. The East Asian Paradox - Thieme Connect
In this article, we propose updated evidence and future directions of antithrombotic treatment in East Asian patients.
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2. [PDF] 1. A calculation method of nitrogen column length for controlling ...
26 nov 2021 · A calculation method of nitrogen column length for controlling annular overpressure in underground gas storage (UGS) wells with intensive ...
3. [PDF] arXiv:2105.06261v3 [hep-ph] 28 Oct 2021
28 okt 2021 · We have used the dynamically constrained phase space coalescence model to study the production of the exotic state X(3872) based on the ...
4. TRABID inhibition activates cGAS/STING-mediated anti-tumor ...
26 mei 2023 · Here the authors report a role for the deubiquitinating enzyme TRABID in regulating mitotic cell division and suppressing anti-tumor immunity, ...See AlsoCrunchyroll His Majesty's Secret Heroine Episode 7Über 60 Prozent Rabatt auf E-Bikes: Aldi reduziert sämtliche Pedelecs stark im Preis - nur noch für kurze ZeitNancy Pazelt ObituarySEMI-PERMANENT EYEBROW TATTOO | cost | before and after photo
Activation of tumor-intrinsic innate immunity has been a major strategy for improving immunotherapy. Previously, we reported an autophagy-promoting function of the deubiquitinating enzyme TRABID. Here, we identify a critical role of TRABID in ...
5. Long noncoding RNA BCRP3 stimulates VPS34 and autophagy ...
10 mei 2022 · Ruei-Liang Yan, Chiu-Lin Luan, Chun-Chieh Liao, Li-Heng Liu, Fei-Yun Chen & Ruey-Hwa Chen. Institute of Molecular Medicine, College of ...
Autophagy plays important roles in cell homeostasis and protein quality control. Long non-coding RNAs (lncRNAs) have been revealed as an emerging class of autophagy regulators, but the majority of them function in regulating the expression of autophagy-related genes. LncRNAs that directly act on the core autophagic proteins remain to be explored. Immunofluorescence staining and Western blotting were used to evaluate the function of BCRP3 in autophagy and aggrephagy. RNA immunoprecipitation and in vitro RNA–protein binding assay were used to evaluate the interaction of BCRP3 with its target proteins. Phosphatidylinositol 3-phosphate ELISA assay was used to quantify the enzymatic activity of VPS34 complex. qRT-PCR analysis was used to determine BCRP3 expression under stresses, whereas mass spectrometry and Gene Ontology analyses were employed to evaluate the effect of BCRP3 deficiency on proteome changes. We identified lncRNA BCRP3 as a positive regulator of autophagy. BCRP3 was mainly localized in the cytoplasm and bound VPS34 complex to increase its enzymatic activity. In response to proteotoxicity induced by proteasome inhibition or oxidative stress, BCRP3 was upregulated to promote aggrephagy, thereby facilitating the clearance of ubiquitinated protein aggregates. Proteomics analysis revealed that BCRP3 deficiency under proteotoxicity resulted in a preferential accumulation of proteins acting in growth inhibition, cell death, apoptosis, and Smad signaling. Accordingly, BCRP...
6. Exploring the effect of humor in robot failure - IDEAS/RePEc
... current research focuses on whether humor could be an effective recovery ... Chen, Nuoya & Mohanty, Smaraki & Jiao, Jinfeng & Fan, Xiucheng, 2021. "To ...See AlsoPC WATCH BY JOHN RAY
Service robots are playing an increasing role in tourism and hospitality. However, this advanced technology is not immune to mistakes. The current research focuses on whether humor could be an effecti
7. Entrepreneurial Leadership Camp | CEIBS
2021/9, Shanghai, China, Industry Restructuring: Innovative Organization ... Chen,Fangyi. Meiyou. Chen,Weixing. FunCity. Gao,Yu. MySoft. Ge,Qiong. Fortune Tech ...
In 2012, CEIBS pioneered the first entrepreneurship programme "CELC" in China, which is intended to identify the most promising local entrepreneurs and help them see further, develop a global vision, and create an innovation and entrepreneurship ecosystem by providing them with the best entrepreneurial guidance.
8. Vol 9, No 1 (January 15, 2021) - Annals of Translational Medicine
Xi Chen, Yuan-Liang Yan, Shuang-Shuang Zeng, Zhi-Cheng Gong, Zhi-Jie Xu. Annals of Translational Medicine. 2021;. 9. (1). :47. | https://dx.doi.org/10.21037/atm ...
The Annals of Translational Medicine’s specific areas of interest include, but not limited to multimodality therapy, biomarkers, imaging, biology, pathology, and technical advances related to medicine.
9. NIR-II emissive anionic copper nanoclusters with intrinsic ...
1 jun 2024 · Chen H, et al. Visible light gold nanocluster photocatalyst ... 2021;143:10560–10564. doi: 10.1021/jacs.1c05019. [DOI] [PubMed] [Google ...
Ultrasmall copper nanoclusters have recently emerged as promising photocatalysts for organic synthesis, owing to their exceptional light absorption ability and large surface areas for efficient interactions with substrates. Despite significant ...
